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January 20, 1993

National Registry Seeks Scarce Data on Pregnancy Outcomes During Chemotherapy

JAMA. 1993;269(3):323. doi:10.1001/jama.1993.03500030015003

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THE EFFECTS of chemotherapy on a developing fetus can never be ascertained by. experiment—researchers would never purposefully expose a group of pregnant women to these agents. This lack of data, however, makes counseling difficult on the rare occasions when a pregnant woman needs chemotherapy to save her life, or when she discovers her pregnancy while she is undergoing chemotherapy.

To assist pregnant women and their physicians during these urgent and critical situations, the National Cancer Institute, Bethesda, Md, set up a computerized database in 1985 to glean as much knowledge as possible from the outcomes of pregnancies exposed to anticancer agents.

Now at Pittsburgh  Today, the registry has grown to 274 cases and is maintained at the University of Pittsburgh (Pa) Genetics Institute. Its organizers encourage health care providers who would like to register a case or obtain information from the database to call (412) 641-4168 during business hours Eastern