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March 28, 1986

Hemotherapy of the Infant and Premature

Author Affiliations

University of Illinois College of Medicine Chicago

JAMA. 1986;255(12):1638. doi:10.1001/jama.1986.03370120116039

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This handy monograph from the American Association of Blood Banks presents a state-of-the-art summary of transfusional problems and therapy in the premature and full-term neonate. Although the outgrowth of an American Association of Blood Banks technical workshop, the monograph deserves a much broader pediatric audience, especially among house staff, students, and neonatology fellows who all too frequently do not consider transfusion therapy the science that it is. Approximately half of the monograph is written by expert pediatricians who are involved in direct patient care.

The initial chapter provides useful tables of normal values, which change so rapidly during this critical period of life. The unique interactive physiology and pathophysiology of the neonate and of fetal hemoglobin and the erythrocyte are concisely reviewed. Then follows a discussion of the indications for erythrocyte transfusion and a review of the metabolic considerations of anticoagulants, storage, and effects in transfusion into the sick or