April 11, 1986

Haemophilus parainfluenzae Liver Abscess in a Recipient of a Renal Transplant Who Had Polycystic Disease

Author Affiliations

Department of Medicine Yale University School of Medicine New Haven, Conn

JAMA. 1986;255(14):1878. doi:10.1001/jama.1986.03370140076015

To the Editor.—  Renal cyst infections are common in patients with autosomal dominant polycystic kidney disease (PCKD).1 In contrast, liver cysts, present in 30% of patients with polycystic kidney disease,2 rarely become infected and when they do, enteric organisms are isolated.3 We report a patient with polycystic kidney disease who, after undergoing kidney transplantation, experienced a liver cyst infection with Haemophilus parainfluenzae. She was successfully treated with percutaneous drainage of the abscess and a one-month course of ampicillin.

Report of a Case.—  A 57-year-old woman with polycystic kidney disease and renal failure underwent cadaveric renal transplantation eight months before admission. Immunosuppressive therapy initially consisted of cyclosporine (10 mg/kg/day) and prednisone (30 mg/day). The patient experienced hepatitis B virus infection during the third month after transplantation, with persistent hepatitis B surface antigenemia. An abdominal ultrasound mixed-fraction examination showed several liver cysts. Six weeks before the current admission (6 1/2