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April 18, 1986


Author Affiliations

Groupe Hospitalier Pitié-Salpêtrière Paris

JAMA. 1986;255(15):2024-2025. doi:10.1001/jama.1986.03370150066018

To the Editor.—  Some aspects of the epidemiology of sarcoidosis remain obscure. Herein we summarize the epidemiologic data obtained from a French retrospective multicentric study.1 The diagnosis of sarcoidosis was based on the criteria redefined at the Seventh International Conference on Sarcoidosis and Other Granulomatous Disorders.2The mean age at diagnosis, established in 384 patients, was 38.9 years. Among 505 patients, 216 (43%) were men and 289 (57% ) were women. The female-to-male sex ratio was 1.4. The percentage of patients developing sarcoidosis before age 40 years was 57%. The Figure indicates the age-specific incidence in men and women. The mean age at diagnosis was higher in women than in men (41.4 years vs 35.5 years, P<.001). The female-to-male sex ratio was 0.97 in those younger than 40 years and 2.51 in those older than 40 years (P<.001). In patients with unusual involvement (cardiac, renal, neuromuscular), the