Pioneering development of the plasma-derived and yeast-derived recombinant hepatitis B vaccines represents a major contribution to preventive health care of this century. Current and expanding worldwide application of hepatitis B vaccine promises to eliminate and eventually eradicate hepatitis B infection from the human population and, with it, many cases of cirrhosis and cancer of the liver.
Douglas RG. The Heritage of Hepatitis B Vaccine. JAMA. 1996;276(22):1796-1798. doi:10.1001/jama.1996.03540220020011