—To determine the relationship between human leukocyte antigen (HLA) loci and restenosis after percutaneous transluminal coronary angioplasty (PTCA).
Design and Setting.
—Cross-sectional study in patients treated by PTCA at Juntendo University Hospital, Tokyo, Japan.
—A total of 65 patients (58 males and 7 females) with coronary artery stenosis who were consecutively selected between October 1994 and June 1995.
Main Outcome Measures.
—Significant relationships between the restenosis and the HLA-Cw1
—Among HLA-C locus, Cw1 was negatively related to restenosis (multivariate adjusted odds ratio, 0.19; 95% confidence interval, 0.06-0.63; P=.007).
—In HLA typing, Cw1 may be a useful marker for the prediction of restenosis after PTCA.
Watanabe Y, Yamada N, Yokoi H, Fujiwara Y, Mokuno H, Daida H, Yamaguchi H. Relationship Between HLA-C Locus and Restenosis After Coronary Artery Balloon Angioplasty. JAMA. 1997;277(12):983-984. doi:10.1001/jama.1997.03540360051030