by Guido Majno and Isabelle Joris, 974 pp, with illus, $75, ISBN 0-86542-372-5, Cambridge, Mass, Blackwell Science, 1996.
Professor Majno is a foremost philosopher-pathologist in the company of Drs Oliver Wendell Holmes, Claude Bernard, Lewis Thomas, and Ruy Pérez-Tamayo. Dr Joris is a productive bioscientist and specialist in inflammatory and vascular phenomena, exemplified in sparkling chapters. Their book is replete with excellent original or borrowed gross and photomicrographs, 27 color plates, x-rays, scans, electron micrographs, immunohistochemical tests, and many outstanding original or adapted diagrams of cells and tissue reactions, graphs, flow charts, and tables that make splendid learning and teaching aids. Some 4500 references are provided, from the time of Hippocrates to the present, quite a few from 1995 and 1996, which takes some doing.
Pathobiology examines how and why abnormalities develop, using animal and plant models, cell and tissue cultures, and biologic and biochemical experiments. Philosophers of medicine are rare and to be cherished, for most practicing pathologists have little time to dream. In Cells, Tissues, and
Sommers SC. Cells, Tissues, and Disease: Principles of General Pathology. JAMA. 1997;277(14):1170-1171. doi:10.1001/jama.1997.03540380084041