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June 11, 1997

Fiber Intake and Risk of Developing Non—insulin-dependent Diabetes Mellitus

Author Affiliations

Chicago Center for Clinical Research Chicago, Ill

JAMA. 1997;277(22):1761. doi:10.1001/jama.1997.03540460027022

To the Editor.  —In their article, Dr Salmerón and colleagues1 present data that support the concept that consumption of a diet with a high glycemic load and/or low in fiber is associated with increased risk for the development of non—insulin-dependent diabetes mellitus (NIDDM) (type II) in women. In their analyses, the authors considered total dietary fiber, as well as fiber from fruits, vegetables, and cereals.In a previous report, written by some members of the same research group, men in the highest quintile of total dietary fiber intake had a relative risk (RR) of 0.69 (95% confidence interval [CI], 0.54-0.88) for coronary mortality.2 This relationship remained statistically significant after adjustment for several potential confounders. In addition, soluble dietary fiber intake was somewhat more strongly associated with coronary events (RR, 0.63; 95% CI, 0.50-0.80, for the highest vs lowest quintile) than total or insoluble fiber consumption. Thus, a 3-g/d