To the Editor.
—The state of Maryland, as part of the Centers for Disease Control and Prevention's national surveillance for human immunodeficiency virus (HIV) variants, collects blood from a sample of persons with acquired immunodeficiency syndrome (AIDS) for determination of viral subtype. Two patients infected with HIV-1 variants have been identified: the first identified HIV-1 subtype G infection in the United States, and the second identified HIV-1 group O infection in the United States.1Patient 1 was a woman in her mid 30s who was born in West Africa; HIV infection was diagnosed in the United States in the early 1990s. The patient was likely exposed to HIV by heterosexual contact with an HIV-infected person in Africa. She had severe immunosuppression and AIDS-defining opportunistic illnesses, including recurrent pneumonia, esophageal candidiasis, toxoplasma encephalitis, and disseminated cytomegalovirus disease. Death was attributed to HIV disease, pancytopenia, and cavernous sinus thrombosis.Plasma from
Sullivan PS, Do AN, Robbins K, Kalish M, Subbarao S, Pieniazek D, Schable C, Afaq G, Markowitz J, Myers R, Joseph JM, Benjamin G. Surveillance for Variant Strains of HIV: Subtype G and Group O HIV-1. JAMA. 1997;278(4):292. doi:10.1001/jama.1997.03550040048035