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September 17, 1997

Bioequivalence of Levothyroxine Preparations: Issues of Science, Publication, and Advertising

Author Affiliations

Denver, Colo

JAMA. 1997;278(11):897. doi:10.1001/jama.1997.03550110035022

To the Editor.  —I read with interest the controversy1 surrounding the article2 comparing different thyroid medications. While I find suppression of valuable clinical information to be deplorable, the other point of view also must be expressed.Some people pay for research because they want the answers to specific questions. The research is not carried out for any particular reason other than that the person funding the research wants the answer. If a contract is signed between 2 individuals to have such research carried out, there is no implicit guarantee that the researcher will have the authority or ability to publish this contracted research. I am responsible for significant amounts of contracted historical research. Some of this work has been published and some has not. I do not expect my local researchers to publish their parts of my projects.While I have never suppressed publication of medical research that I have sponsored