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Editor Journal of the American Medical Association:
I have been much interested in reading the report of the German Commission appointed to investigate this important question. Careful clinical observation satisfied me years since that humanized virus has equal, if not greater, protective power than bovine virus; that it is attended with less severe constitutional disturbance, and produces fewer ugly pustules, regardless of the agency whence the bovine virus came.The syphilitic scare has no terrors for me, although a London enthusiast appears to have settled affirmatively the question of its possibility. With ordinary care it is practically impossible to convey such taint by means of vaccine lymph; while with extraordinary caution in securing healthy virus the danger of conveying any disease other than the one for which you vaccinate, has, in my judgment, no foundation in fact.It is true that latent impurity in the system may become manifest by
Chase SB. HUMANIZED OR BOVINE VIRUS IN VACCINATION.. JAMA. 1885;IV(7):193-194. doi:10.1001/jama.1885.02390820025015