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For some months innumerable articles have appeared in current medical literature discussing the physiological and therapeutic action of antipyrin. That the drug has a wide range of usefulness is an undoubted fact and yet many practitioners who welcomed it gladly at first are now regarding it with some suspicion because of the occasional toxic effects that they observe from it and with some misgivings because of the failure to obtain expected results from its use. There is little doubt but that the drug will obtain a permanent place in therapeutics but we need much more exact information in regard to the indications for its use. It is surprising, as Friedländer points out in a late number of the Therapeutische Monatshefte, that among so many articles describing the action of the drug so few have appeared which consider its usefulness in diseases of children. Friedländer has observed with care the indications
ANTIPYRIN IN ACUTE BRONCHITIS OF CHILDREN.. JAMA. 1887;IX(16):499-500. doi:10.1001/jama.1887.02400150019005