This condition, while not common, is yet met with sufficient frequency to warrant a careful study of the cases coming under observation. It generally attacks men in the most active period of their life, between the ages of 25 and 40. No cases, so far as I have been able to find in the literature, have been reported in women. Several cases have been studied with sufficient thoroughness to furnish a good illustration of the pathology.
—Man, aged 38, single; a carpenter; has had all the diseases of childhood. He has also had gonorrhea; he drinks alcoholics moderately, but has been a cigarette "fiend" for twenty years.
—April, 1905, the toes on the left foot began to burn, became red and when he walked they cramped and drew up. This condition continued until about November. When he was at rest he did not suffer, but the burning
ALLEN CW. PERIPHERAL OBLITERATIVE ENDARTERITIS.. JAMA. 1908;L(8):606–607. doi:10.1001/jama.1908.25310340034002c