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June 6, 1908

Arterial Hypertonus, Sclerosis and Blood Pressure.

JAMA. 1908;L(23):1922. doi:10.1001/jama.1908.02530490050023

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The first chapter of this interesting and instructive book deals with the structure and movements of arteries and with blood pressure and its relation to contraction of vessels and power of the heart. The author's discussion of methods of measuring blood pressure or rather as he rightly contends vessel compressibility is excellent. He recognizes the following anatomical changes in arteries: Atheroma, obliterative endarteritis, calcareous infiltration and arteriosclerosis, limiting the last to generalized arterial thickening without the degeneration of atheroma. But his interest centers in the changes in the wall of arteries produced by contraction of them and called by him hypertonus. This condition he shows is quite as often manifest in arteries which are structurally diseased as in those that are normal. The hypertonus may be due to the influence of the nervous system but oftener to the condition of the blood, i. e., to toxic matter in it. The

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