The question of most importance in all operative surgery is how to save human life, not only for the time, but to prevent a return of the morbid process whenever this is possible. Certain problems regarding the extension of malignant disease have engaged the attention of physicians for many years, and we have been impressed with the importance of further study of the danger of implantation of cancer and tuberculosis during the time we have a broad exposure of raw surfaces, as during breast and pelvic dissections; as, indeed, any wound may be involved directly, or may be the port of entry of further extension of the disease in question.
I wish to call attention to certain cases in which carcinoma, sarcoma and tuberculosis have apparently made fresh and rapid extension after operations. This immediate invasion appears to indicate a close relation of cause and effect. My observations lead me
STONE IS. INFECTION OF OPERATIVE WOUNDS BY MALIGNANT DISEASE.. JAMA. 1908;LI(9):748-750. doi:10.1001/jama.1908.25410090030001j