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December 26, 1908


JAMA. 1908;LI(26):2220-2221. doi:10.1001/jama.1908.02540260022005

Of late years the treatment of exophthalmic goiter has received a marked degree of attention from clinicians and surgeons alike. The results of serum therapy have been favorable in a considerable series of cases, but so great has been the success of surgical treatment that the tendency has become rather widespread to advise operation in all patients not relieved by medical aid and in many without ever giving the newer therapeutic measures a trial. That this may prove in some instances a most unwise procedure is strongly suggested by some recent German publications.1

Capelle has found the presence of an enlarged or persistent thymus a frequent occurrence at autopsy on patients developing "delirium cordis" and dying within twenty-four hours after operation for exophthalmic goiter—so frequent, indeed, that in the absence of other positive findings it assumes considerable etiologic importance It has been customary to assign such deaths to toxemia

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