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In almost all parts of the world it is the universal experience that the chief local cause of blindness is still pus infection of the eyes of new-born children. Yet it was more than a quarter of a century ago that the careful and scientific experiments of Carl S. F. Crede, then widely known as a successful obstetrician of Leipzig, gave to the world a prophylactic at once simple, safe and inexpensive, which if it had since that time been universally employed would have saved the eyes of numberless thousands who because of this neglect have passed their lives in darkness. There is no doubt whatever that through the unremitting efforts which have been made by physicians and others, and more especially during the last few years, the number of infections due to this cause, and consequently the amount of blindness resulting from these infections, has been materially diminished. But
Lewis FP, Harper CA, Pease HD. OPHTHALMIA NEONATORUM AND ITS PREVENTIONREPORT OF THE COMMITTEE ON OPHTHALMIA NEONATORUM OF THE AMERICAN PUBLIC HEALTH ASSOCIATION. JAMA. 1909;LII(11):876-881. doi:10.1001/jama.1909.25420370034003a