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April 3, 1909


Author Affiliations

Lecturer on Tropical Diseases, Medical Department, Vanderbilt University NASHVILLE, TENN.

JAMA. 1909;LII(14):1093-1096. doi:10.1001/jama.1909.25420400019001g

It is my purpose to make a brief review of sixty-eight cases of typhoid fever and the findings, by blood cultures, with special reference to the mild atypical forms. The study of these fevers, and the results obtained through blood cultures, is of great practical import. It clears them from the haze of doubt and places them at once where they properly belong. Many observers — Osler,1 Dock, Vaughan2 and others — have believed for a long time that these indefinite fevers would ultimately prove to be typhoid infections, and a great deal of clinical evidence has been brought forward in support of this belief, but it has not been sufficiently definite to satisfy all.

In 1908 I had published an article3 in which I had studied clinically 200 cases of typhoid, with the idea of clearing up these indefinite forms. I gave in that paper evidence

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