The physician has possibly no more irritating sense of helplessness than when called to treat a patient with whooping cough. Besought from day to day by a distressed mother for a greater measure of relief, he tries one and another drug, only to realize the inadequacy of them all.
A perusal of the literature demonstrates that quinin, despite all the newer drugs, holds its own. More than a year ago, in looking over some literature on the subject, the proposition to bring quinin for its germicidal effect into immediate contact with the respiratory mucous membrane, attracted my attention.
Michael, forty years ago, recommended the insufflation of quinin and benzoin powder into the nostrils. Litzerich mentions in Ziemssen's Encyclopedia that he tried an inhalation of a solution of sulphate of quinin in one case, but that the child was removed from the hospital too soon for any conclusions to be drawn.
MASLAND HC. QUININ INHALATIONS IN PERTUSSISWITH A CONSIDERATION OF OTHER PETROX MEDICAMENTS. JAMA. 1909;LII(23):1832-1833. doi:10.1001/jama.1909.25420490028003a