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Article
October 9, 1909

COMPLEMENT FIXATION WITH LECITHIN AS ANTIGEN IN PELLAGRAA PRELIMINARY NOTE

Author Affiliations

NEW ORLEANS

JAMA. 1909;LIII(15):1187. doi:10.1001/jama.1909.92550150042002a

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Abstract

The original Wassermann reaction and its many modifications, though at first thought to be specific for syphilis, has been found in a number of other diseases that are all known, or thought, to be of protozoan origin. The reaction seems, then, to be limited to protozoan diseases with the exception of a few cases of advanced tuberculosis and leprosy.

The generally accepted theory of the etiology of pellagra the world over is that it is poisoning from eating improperly cured or diseased corn products. Lombroso extracted from spoiled corn an oil and other extractives with which he produced experimentally in animals a disease very similar to, or identical with, pellagra. In Italy, where there is much pellagra, the authorities have reduced the amount of the disease to less than onefourth of what it was when the regulation against the use of diseased corn was begun. The work has been

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