It is the object of this paper to present an abstract of the present knowledge of the physiology of the glands that furnish internal secretions; of the clinical conditions that disturbances of these glands are known to cause; of abnormal clinical conditions that disturbances of these glands are sometimes considered to cause; of the influence that can be exerted on the secretion of these glands by drugs and preparations of glands; and of the different physiologic activities that can be caused by the administration of gland preparations.
The glands to be considered are those that are known to furnish secretions which do not reach the blood and lymphatics by ducts. They are the pituitary (hypophysis cerebri), the thyroid, the parathyroids (epithelial bodies), the pancreas, the suprarenals (adrenals), the ovaries, and the testicles.
Also should be considered the glands and organs which have been assumed to furnish internal secretions
OSBORNE OT. DISTURBANCES OF THE INTERNAL SECRETIONS CLINICALLY CONSIDERED. JAMA. 1910;LIV(9):670-676. doi:10.1001/jama.1910.92550350001001a