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To the student of hematology the name of William Hunter is well-known. Some twenty years ago he described the iron-containing pigment deposits in the liver of pernicious anemia and their relation to processes of blood destruction. A little later he called attention to the occurrence of glossitis as an important clinical manifestation of this disease and to its probable causal relation to gastritis and enteritis with resulting hemolysis in the portal system. Since then he has repeatedly emphasized these views and in 1900 he embodied the substance of his previous communications in a monograph on pernicious anemia.
The present book is announced as the first volume of a work on "Severest Anemias." Hunter's views have become more definitely crystallized and he speaks with no uncertain tone. Pernicious anemias, he says, since the time of Biermer, has been a promiscuous grouping of ill-understood anemias, including several kinds that are etiologically, pathologically
Severest Anemias.. JAMA. 1910;LIV(9):728. doi:10.1001/jama.1910.02550350064017