It is the purpose of this paper to restate the principle of anoci-association as applied to surgical operations, to describe its application, and to present the results of operations by this method as compared with an equal number of operations performed by other methods.
My argument assumes that physical action and emotional activity are only expressions of motor stimulation; it assumes that there are in every active animal and in man stores of energy which when released are expressed in motion or emotion; that when these stores of energy are consumed fatigue or exhaustion is produced. The stored energy of the body may be discharged by physical injury of sensitive parts of the body, by emotional excitation or by physical exertion.
It is of highest importance to know that inhalation anesthesia does not prevent injury impulses from reaching the brain-cells and making them discharge their nervous energy, thus causing exhaustion
CRILE GW. THE RESULTS OF OPERATIONS, ESPECIALLY ABDOMINAL, PERFORMED ON THE PRINCIPLE OF ANOCIASSOCIATION. JAMA. 1912;LIX(2):114-116. doi:10.1001/jama.1912.04270070115012