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The material for this report was derived from the histories of 150 cases of pulmonary tuberculosis treated with tuberculin at the Rhode Island State Sanatorium during the five years 1907 to 1912 inclusive.
In this series of cases tuberculin was not usually given to incipient or far advanced patients. The usual type of patient selected was the chronic one whose disease had been arrested or improved, but who was still having tubercle bacilli in the sputum with a moderate amount of signs. Tubercle bacilli had been present at some time in 132, or 88 per cent., of the cases. Only three or four had cavity signs. In a few cases, however, tuberculin was tried in those who had completely failed to improve under the usual hygienic-dietetic régime and who had sufficient temperature to indicate an active process The tuberculin was given after the manner advocated by Trudeau, an effort being
BARNES HL. REPORT OF 150 CASES OF PULMONARY TUBERCULOSIS TREATED WITH TUBERCULIN. JAMA. 1912;LIX(5):332-333. doi:10.1001/jama.1912.04270080014005