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August 3, 1912


JAMA. 1912;LIX(5):358-359. doi:10.1001/jama.1912.04270080040012

No one drug has come into general use as a germicide with such universal satisfaction as iodin. Its virtues are so well known in surgery as to require no comment.

I began the use of this drug in 1878 when I commenced my researches in interstitial gingivitis. As a mouth antiseptic and germicide it acts more quickly and more satisfactorily than any other drug. The objection to the use of the official preparation, which contains 7 per cent. iodin dissolved in alcohol to which is added 5 per cent. potassium iodid, is due to the fact that frequent applications will destroy the mucous membrane of the mouth. To obviate this, I prepared the following and called it iodoglycerole:

Water... 2 parts

Zinc iodid... 3 parts

Iodin (crystals)... 5 parts

Glycerin... 10 parts

As compared with the ordinary tincture of iodin, its astringent properties are greatly increased; the glycerin causes rapid

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