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Article
August 24, 1912

EXPERIMENTAL DEVASCULABIZATION OF SEGMENTS OF INTESTINE WITH AND WITHOUT MECHANICAL OBSTRUCTION

Author Affiliations

RICHMOND, VA.

JAMA. 1912;LIX(8):597-599. doi:10.1001/jama.1912.04270080279004
Abstract

Any experimental work dealing with intestinal obstruction as one of its chief features requires a preliminary statement of the presentstatus of obstruction. The exact cause of death in obstruction of the bowel has never been definitely determined. The three theories advanced are: (1) the nervous theory, which holds that the nervous system is affected in somewhat the same way as in shock; (2) the bacterial theory, which holds that death is due to the bacteria contained in the obstructed intestine; (3) the toxemia theory, which holds that death in obstruction is due to some perversion of intestinal metabolism. Metabolic toxins may be formed in the epithelium of the intestine, or the mucosa may permit the direct absorption of peptones and products from the intestine that are normally changed by the epithelium before being discharged into the circulation. The nervous theory has few advocates, but the bacterial theory and the theory

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