Aside from the appearance of macrophagocytes in artificially induced effusions in animals, little has been written on their presence in the human body.
Metchnikoff1 called attention to the presence of these elements in the peritoneal cavity of a guinea-pig into which had been injected the red corpuscles of a goose; the macrophagocytes seemed to be the chief factor in the resorption of the foreign corpuscles.
Van Nuys2 reported the case of a patient whose blood contained large numbers of mononucleated and multinucleated basophilic cells, ingesting the white corpuscles. At times they numbered as high as 40 per cent, of all the white cell elements of the blood. Actual measurement showed them to average 23 by 16.9 microns.
Bartlett3 reported a case exhibiting the same character of cell in the lobes of the ear, which were markedly cyanotic. The tops of the ears and the general circulation did
Pottenger JE. MACROPHAGOCYTES IN THE SPUTUM OF A PATIENT WITH CHRONIC HEMOPTYSIS. JAMA. 1912;LIX(20):1794-1795. doi:10.1001/jama.1912.04270110208012