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Article
November 30, 1912

THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1912;LIX(22):1974-1979. doi:10.1001/jama.1912.04270110388015
Abstract

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SATURDAY, NOVEMBER 30, 1912

THE NERVOUS SYSTEM AND METABOLISM  The muscles, the secretory glands and the central nervous system preeminently represent the physiologically active tissues of the organism. Their function exhibits itself in the familiar manifestations of movement, secretion and cerebration, respectively; but in the case of the muscles and glands, at least, there are well-known attendant phenomena characteristic of most physiologic activities in which a transformation of energy is concerned. Heat is evolved and results in a transitory rise of temperature of the individual tissue or even the organism as a whole; carbon dioxid is eliminated in greater amounts, and this waste product serves as an index of the augmented chemical transformations going on, while most striking of all, perhaps, is the increased consumption

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