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Under this head Dr. Frank C. Bressler, of Baltimore, has a brief communication in the Therapeutic Gazette for April, 1889, in which he refers the primary seat of shock to the nervous centers in the medulla oblongata. He claims that shock is not only a depression of the circulation, but in every case involves the cardiac, respiratory, vaso-motor and secretory centers, so far as they exist in the medulla oblongata, and consists in a sudden molecular disturbance in those centers of greater or less severity. It is not claimed that all these centers are equally disturbed in every case of shock. On the contrary, in some cases the cardiac and vaso-motor functions are chiefly affected, and in others the respiratory suffer most, as it did in the case related by Dr. Bressler; and in choosing remedies we should be guided by the special predominating feature of each case. The correctness
ATROPINE AS A REMEDY FOR SHOCK.. JAMA. 1889;XII(18):631-632. doi:10.1001/jama.1889.02400950019006