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Diseases of the orbit present a very interesting group. They are very numerous, considering the size of the orbital cavity and its somewhat isolated location. Here we find tumors malignant and non-malignant originating in the orbit itself, in the optic nerve, in the globe, and afterwards invading the orbital cavity, as well as growths from the nasal fossae and the cerebrum, which encroach on it from different directions. Each one of these subjects might well command our earnest attention, but I propose to mention one class only, tumors of the optic nerve. They are comparatively rare, there being at present less than seventy cases on record. With your permission I will give a hasty résumé of the literature at my command on the subject, and then give in detail the two cases which have come under my observation.
In Vol. xxv, Graefe's Archiv, Dr. Willemer, of Göttingen, reports twenty-two cases
AYRES SC. TUMORS OF THE OPTIC NERVE, WITH REPORT OF TWO ORIGINAI, CASES.Read in the Section of Ophthalmology at the Fortieth Annual Meeting of the American Medical Association, June, 1889.. JAMA. 1890;XIV(10):325–331. doi:10.1001/jama.1890.02410100001001