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January 21, 1911

Sodium Cacodylate in Syphilis

Author Affiliations

New York City.

JAMA. 1911;LVI(3):211. doi:10.1001/jama.1911.02560030047026

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To the Editor:  —Dr. A. T. Caffrey becomes enthusiastic over sodium cacodylate in syphilis (The Journal, Dec. 24, 1910, p. 2211), because by this drug he has healed (?) a syphilitic lesion of the lip in twenty days, though the patient still possesses evidences of a hard chancre and is still under treatment.In our cases at Dr. F. Bierhoff's clinic, luetic sores on lip and elsewhere heal very rapidly under the action of the soluble salts of mercury (oxycyanid), rarely consuming a larger period than two weeks, intramuscular injections being used in ascending dosage and patient seen every other day.It is inconceivable that a patient with such a strong arsenical breath as described by Dr. Caffrey should display no disagreeable symptoms. To my mind, it is a classical symptom of poisoning—it is well to remember that arsenical poisoning is a very insidious process and a persistence of arsenic under

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