Notwithstanding the fact that Ehrlich says that the preliminary stage has been closed, one receives the impression from the recent literature on 606 that there are many points still to be settled in almost every phase of the work with this new remedy especially in regard to its administration, prognosis, indications and by-effects. We stand at the beginning of our work; many questions need elucidation, and it is of general interest that results should be collected from many different sources.
The difficulty of following the technic according to the directions enclosed with salvarsan is apparent, for here one is told vaguely to use an intravenous method, a neutral suspension or an alkaline solution. At the present writing, the intravenous and the alkaline solution methods are the most popular in European clinics, but still each clinician is endeavoring to push his own method regardless of whether or not the other method
CORBUS BC. OBSERVATIONS ON TWENTY-EIGHT PATIENTS TREATED WITH THE EHRLICH-HATA REMEDY (SALVARSAN). JAMA. 1911;LVI(8):566-573. doi:10.1001/jama.1911.02560080014004