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Article
February 26, 1916

TRANSFUSION OFBLOOD WITH SPECIAL REFERENCE TO THE USE OF ANTICOAGULANTS

Author Affiliations

NEW YORK

From the Laboratory of Clinical Pathology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York.

JAMA. 1916;LXVI(9):618-624. doi:10.1001/jama.1916.02580350006002
Abstract

We previously reported1 a method of transfusing blood by means of specially constructed pipets and cannulas designed for use with either a lining of hardened paraffin or a preliminary internal coating of an anticoagulant solution such as leech extract or herudin2. During the past eighteen months we have experimented with various anticoagulants other than paraffin and herudin, with a view to determining the best anticoagulative agents for purposes of transfusion. We desire here to report the results of these experimental transfusions and to summarize the theoretical and practical advantages of the anticoagulants which we have studied; and in order to make more evident at the outset the practical bearing of this study, we propose, first, to discuss briefly the present status of blood transfusion as a rational therapeutic procedure, and to call attention to certain aspects of this problem which are not usually taken into consideration. It is

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