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THE NECESSITY OF TAKING NOSE CULTURES IN THE DETECTION OF DIPHTHERIA CARRIERS
During the month of October, 1915, cases of diphtheria occurred in six different schools in widely separated communities of California. Among the measures used to control the disease was the taking of cultures from all contacts and the subsequent isolation of all carriers. The proportion of infected to the noninfected contacts in such outbreaks of diphtheria has been subject to great variation, and while the uniform taking of nose cultures with those from the throat will not appreciably reduce this variation, it will reduce to a minimum the missing of carriers. A study of the comparative statistics in this article, in which the personal equation has been eliminated by three persons making the examinations with checking of results, and only typical granular type of diphtheria bacilli being considered positive, proves absolutely that if we are to control epidemics
GEIGER JC, KELLY FL, BATHGATE VM. DIPHTHERIA CARRIERS. JAMA. 1916;LXVI(9):645-646. doi:10.1001/jama.1916.02580350033012