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Article
May 5, 1888

RELATION OF SCROFULOUS GLAND DISEASE TO OTHER FORMS OF TUBERCULOSIS.

JAMA. 1888;X(18):559-560. doi:10.1001/jama.1888.02400440019006

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Abstract

Mr. Frederick S. Eve has recently published a series of experiments (in the British Medical Journal, of April 14, 1888) undertaken for the purpose of determining the relation of scrofulous gland disease to other forms of tuberculosis. It will be remembered that some experiments by M. S. Arloing appeared to prove that inoculation with material from scrofulous glands was innocuous to rabbits, while it produced general tuberculosis in guinea pigs. From his experiments he inferred that either scrofula and tuberculosis were nearly allied affections, but caused by different agents, or they were derived from a single virus, of which the activity was modified in the scrofulous form.

Mr. Eve's experiments were made with small fragments of the glands prepared with sterilized instruments, "and the possibility of infection of the animals with true tuberculosis was negatived by the precautions taken." In his experiments the inoculations uniformly caused tuberculosis. While he shows

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