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March 11, 1916

Leukemia of the Fowl: Spontaneous and Experimental.

JAMA. 1916;LXVI(11):835. doi:10.1001/jama.1916.02580370055037

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This monograph consists of a review of the limited existing literature on the subject indicated by the title, the report of a single case of the disease occurring spontaneously, and the results of a series of inoculations into other fowls. Its chief importance lies in the fact that it corroborates the reported existence of a disease in fowls resembling closely human leukemia, and transmissible to other fowls by direct inoculation. The existence of such a transmissible disease is important for medical research, since it makes possible experimental work in leukemia. Whether or not fowl leukemia is the same as mammalian leukemia, and especially human leukemia, must still be considered as not entirely settled. There are certain important discrepancies which may or may not be explained as due to differences in the subject rather than the disease; for example, the duration of the disease varies from three to thirty-two days, usually

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