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October 17, 1914

TUBEROUS SCLEROSIS AND OTHER UNUSUAL FEATURES OF EPILEPSY

Author Affiliations

PHILADELPHIA

JAMA. 1914;LXIII(16):1348-1352. doi:10.1001/jama.1914.02570160014004
Abstract

Although epilepsy is a most ancient disease, our knowledge of it in many respects is quite meager. And yet one of the greatest advances ever made in neurology was made with the establishment of the type of this disease which we know as jacksonian epilepsy. While the recognized manifestations of epilepsy are very numerous, there is still much of its etiology that remains a mystery. Of vast importance in the development of many cases is heredity, but the precise extent of the part this plays must always remain uncertain. In some instances we are confident that the cause is encephalitis dependent on the infectious diseases and sometimes it is due to traumatism, syphilis or brain tumor. Occasionally epilepsy is observed to follow fright or other mental shock, but the manner of such influence we cannot understand except as it acts on an individual who is a potential epileptic. Another interesting

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