May 13, 1916


JAMA. 1916;LXVI(20):1540-1543. doi:10.1001/jama.1916.02580460016006

Reports1 have been published of the experimental work which I have performed in sex gland implantations with material taken from dead bodies. The reports comprise certain physiologic and therapeutic observations and conclusions based on the experiments, together with illustrations of the microscopic and histologic results of the implantations. In summary, my various contributions present the following:

  1. For hormone therapy purposes, successful total or partial hetero-implantation of human sex glands in both male and female is practicable. By "successful" implantation, I mean the formation of new blood supply, and a more or less prolonged existence of the gland with coincident hormone production.

  2. The prospect of success from anastomotic implantation—with resulting generative functioning—at present is not brilliant, although possibly not hopeless.

  3. Glands taken from the living subject are most desirable, though rarely obtainable.

  4. Glands taken from the healthy dead body at any time prior to the beginning of decomposition are of

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