As a result of observations made in the medical advisers' office at Cornell University, the writer's attention was attracted to the great prevalence of acne vulgaris and furunculosis among young men. A study of the examination records of the entering students showed that 30.2 per cent. of the freshmen class suffered from acne vulgaris. Of this proportion, the distribution of the lesions in 17.8 per cent. was general and in 12.2 per cent. of the cases it was limited to the facial region.
In order to ascertain just what results could be expected from the different forms of therapeusis, and more especially to try out the efficacy of vaccine therapy in the treatment of acne vulgaris and of furunculosis, an analysis of 100 unselected cases of these two forms of pyogenic dermatoses was undertaken.
The cases were all considered chronic, in that they were all of six months' or more
FOX HH. VACCINE THERAPY AND OTHER TREATMENT IN ACNE VULGARIS AND FURUNCULOSIS. JAMA. 1916;LXVI(26):2064-2067. doi:10.1001/jama.1916.02580520020007