In a report1 to the Surgeon General of the Army dated Sept. 30, 1913, I noted six cases in which the patients were suffering from sprue, all of whom markedly improved under treatment by emetin hydrochlorid (alkaloid) given hypodermically in ½ to 1 grain doses daily for five days. Since then I have observed two more cases and four have been reported to me by other medical officers, in which like results were obtained, making' a total of twelve cases in which the patient's symptoms cleared up under the same treatment. One of these patients had concurrent entamebic dysentery. No case of sprue which has failed to respond to this treatment has come to my attention.
Permanent results were not observed because most of these patients returned to the United States shortly after receiving the treatment. In only one case have I been able to follow the course long
SCHMITTER F. SPRUE TREATED BY EMETIN HYDROCHLORID. JAMA. 1915;LXIV(1):53. doi:10.1001/jama.1915.02570270055014