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The subject of chronic intestinal stasis has become quite popular of late, the term having been popularized by the writings of Lane. In this monograph the author reviews the subject historically, and then enters into an extensive description of the embryology, anatomy, histology and pathology of the large intestine. In discussing the theory of Metchnikoff that not only the appendix but also the cecum and colon are undergoing regression, and that they are not only useless but even harmful organs, the author says, "This appears to be going a little too far, but if it is difficult at least to admit that in a normal state the large intestine is a highly harmful organ it seems to be more admissible that in certain pathological states, particularly when there is a stagnation of the fecal matter, absorption of toxic products may take place from the large intestine and this is a
La Stase Intestinale Chronique. Par le Docteur E. Sorrel, ancien interne, lauréat des Hôpitaux de Paris.. JAMA. 1915;LXIV(1):74. doi:10.1001/jama.1915.02570270076032