It is surely striking that patients with congenital glaucoma apparently disappear from view after a certain length of time; for it is very unusual to find persons with this disease in middle life, though there are some reports of cases in which the process has been spontaneously arrested and some sight retained. That these enlarged eyeballs are extremely susceptible to injury is natural, and unquestionably most of these eyes are enucleated after rupture following often a trivial injury. It is even reported that this rupture can occur spontaneously. Furthermore, the ectatic cornea in these glaucomatous eyes becomes easily infected and stands infection badly, so that a number of the eyes are probably lost from this cause.
I have had an opportunity of observing clinically a case of hydrophthalmia in which a detachment of the retina occurred spontaneously, and the eye then went on to phthisis bulbi. As this outcome is
KNAPP A. RETINAL DETACHMENT IN HYDROPHTHALMIA. JAMA. 1916;LXVII(5):356-357. doi:10.1001/jama.1916.02590050034012