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April 3, 1915


Author Affiliations


JAMA. 1915;LXIV(14):1119-1124. doi:10.1001/jama.1915.02570400001001

The theme of my address is one of entrancing interest to the thoughtful observer, whether from the purely physiologic or the purely clinical point of view. Probably no system of human anatomy, physiology or pathology has been the object of a more intensive study than the cerebrospinal system, from the contributions of the earlier writers to the present day. And yet, with all our knowledge of the anatomy of the brain and spinal cord in their normal state, and of the pathologic processes to which they are subject, how extraordinary it is that of the fluid in which these tissues are forever bathed, so little is known. We are not always, however, to remain in the dark. Hidden truths will soon be revealed, and the year or two just past has been extraordinarily productive. From the many contributions that have appeared in recent times, from the laboratory and clinics of

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