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Article
April 3, 1915

PRACTICAL PHARMACOLOGY

JAMA. 1915;LXIV(14):1155-1158. doi:10.1001/jama.1915.25710400001013
Abstract

XIII 

ANTISEPTICS AND DISINFECTANTS 

DERIVATIVES OF BENZENE—(Continued) 

THERAPEUTIC USES  One part of phenol in five hundred or a thousand parts of water is actively antiseptic for most of the common pathogenic bacteria, and a 1 per cent. solution is actively germicidal for nearly all of the nonsporulating forms, destroying them in a few minutes at ordinary temperatures. Anthrax spores, however, are not destroyed by a 5 per cent. solution in twenty-four hours.Phenol is applied to the skin in dilute solution or preferably as an ointment to relieve itching as in piles. It is also useful as an application to small painful ulcers. The statement is often made that the pain of burns is increased by phenol, but such increase of pain is transient and an anesthetic action is then obtained. Phenol cannot be applied to large surfaces because of the danger of absorption.It is often used as

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