Fever of obscure causation in infants and young children is always of interest, because it is a condition with which we are more or less constantly confronted. The term "obscure causation" is of course used in a relative sense, for it must depend on the number of cases being observed and the diagnostic acumen of the individual observer. Apart from such considerations, however, there will be encountered, from time to time, febrile movements, the causation for which is solved with the greatest difficulty, or sought in vain by the most astute. It is my purpose, not to endeavor to discuss all of the causes of obscure fever in infancy and childhood, but to draw attention to some groups of cases that have given me some trouble during the pastyear.
It seems not amiss at this time to emphasize the rôle of the nervous system in the production of obscure fever,
COPELAND EP. FEVER OF OBSCURE CAUSATION IN INFANCY AND EARLY CHILDHOOD. JAMA. 1916;LXVII(19):1346-1349. doi:10.1001/jama.1916.02590190008003