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May 15, 1915


JAMA. 1915;LXIV(20):1659. doi:10.1001/jama.1915.02570460035016

The blood vessels and the functions associated with them are at present conceived to be dominated in large measure by a nervous control which has its center in the medulla. The behavior of this mechanism, which is responsible for the maintenance of arterial tone and for the regulation of arterial blood pressure, is a matter of everyday importance to the physician. By it the blood supply and, accordingly, the performance of the organs and tissues are influenced in large measure; while many of the drugs which are employed to change the vascular conditions have their actions interpreted from the standpoint of how they influence the vasomotor apparatus. The normal control of the latter is adjusted along with the influence excited by variations in the functions of the heart so as to maintain a blood supply suitable to the needs of the different parts of the organism. It is commonly believed

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