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Article
June 5, 1915

AN UNUSUAL CASE OF GENERALIZED NONPIGMENTED SARCOMAS OF THE SKIN

Author Affiliations

Professors of Dermatology and Syphilology, and Pathology and Bacteriology, Respectively, University of Nebraska, College of Medicine

JAMA. 1915;LXIV(23):1901-1903. doi:10.1001/jama.1915.02570490017008

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Abstract

Sarcoma of the skin appears in several clinical varieties: it may be single or multiple, pigmented, nonpigmented, melanotic or hemorrhagic. It may remain limited to the skin or attack the viscera, and may be either primary or secondary. General primary nonpigmented sarcomatosis of the skin, especially of such rapid and extensive development as in the present case, is sparingly mentioned in textbooks and in the literature, and is sufficiently rare to be of interest.

Considerable confusion exists as to its place as a clinical and pathologic entity. General sarcomatosis is sometimes used as an alternate name for granuloma fungoides, and is by many considered to be related to the latter or to leukemia cutis. Unquestionably there are some cases which form a connecting link between these diseases, but it is beyond discussion that in others no grounds can be found to put them in the same class. In the case

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