From a careful study of seventy cases and from a review of the literature, Ziegler,1 in 1911, felt that one fourth of all cases of Hodgkin's disease, at some time or another in the course of their trouble, showed evidence of skin involvement. Bunting and Yates2 quote Westphal as finding 15 per cent of his cases with skin lesions.
To me, these percentages seemed rather high until I began to go deeper into the subject and look more particularly for these manifestations. After about two years of careful observation of such cases, I feel that these writers are probably correct in their figures. It is my belief that all too frequently cutaneous lesions of lymphogranulomatosis are not noted because they have not been sought after, and it is my object to call the attention of the medical profession to this interesting and as yet not generally recognized series of
COLE HN. THE CUTANEOUS MANIFESTATIONS OF HODGKIN'S DISEASE: LYMPHOGRANULOMATOSIS. JAMA. 1917;LXIX(5):341-348. doi:10.1001/jama.1917.02590320017004