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Article
March 10, 1917

The Pathology of Nephritis as Illustrated by Thirty-Two Consecutive Cases.

JAMA. 1917;LXVIII(10):800. doi:10.1001/jama.1917.04270030132033

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Abstract

This reports a series of thirty-two cases of true diffuse glomerulonephritis, studied carefully at necropsy and with reference to the clinical picture of each case. It is an excellent example of the careful, valuable anatomic work in pathology which has been, on the whole, poorly developed in this country, where greater emphasis has always been laid on experimental methods, largely of necessity through our deplorable lack of necropsy material. No physician can look through Dr. Ophüls' monograph without having a better understanding of the steps in the development of the renal changes nephritis, and perhaps a greater appreciation of the value of thorough anatomic study of even the common diseases. The author reaches these conclusions: Diffuse glomerulonephritis is a disease which may occur in acute, subacute or chronic form. The etiology of the acute and subacute forms is evidently to be found in bacterial infection, and this is quite probably

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