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August 4, 1917


JAMA. 1917;LXIX(5):384. doi:10.1001/jama.1917.02590320060018

Since the early scientific researches of Claude Bernard,1 it has been known that the pancreas is concerned in some way with the utilization of fats in the body. When the fat-digesting properties of the pancreatic juice were duly appreciated, a possible explanation for the phenomenon of suggested interrelationship between the pancreas and fat absorption became available. Lack of pancreatic secretion thus might mean failure of fat digestion and consequent utilization. This is emphasized by the fact that when the pancreatic juice is experimentally diverted from the alimentary tract, fats used in the diet almost invariably appear in the stools, though the failure of utilization is by no means always complete.

Recently it has been suggested that, so far as the utilization of fat is concerned, the mere exclusion of the pancreatic secretion from the intestine is not precisely equivalent to the loss of the entire function of the pancreatic

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